Virology Weekly Newsletter 15.03.2013

Principles of molecular virology Students taking my virology course at the University of Leicester get a weekly newsletter containing extra links relevant to the lectures. This week the class notes are from Principles of Molecular Virology, chapter 7.

 

 

Antiviral drugs

Antivirals versus vaccines

Antivirals versus vaccines

Viruses and Cancer

Viruses and Cancer

NEWS: Receptor for new coronavirus-EMC identified
The cell receptor for the coronavirus-EMC, which has so far infected 15 humans with 9 deaths, has been identified as dipeptidyl peptidase 4 (DPP4). Nice work. Evidence:
- Soluble DPP4 blocks infection of susceptible cells with CoV-EMC.
- Expression of DPP4 in non-susceptible cells renders them susceptible to infection.
- Antibody to DPP4 blocks infection of cells with CoV-EMC.
- Purified DPP4 protein binds CoV-EMC and inhibits infection.

 

 

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