Tag Archives: Biotechnology

Whole Genome Sequencing for Outbreak Detection of Salmonella enterica

Whole genome sequencing is not enough to diagnose and control Salmonella outbreaks. Continue reading

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Gene editing eradicates HIV-1

More than three decades after the discovery of HIV, AIDS remains a major public health problem affecting greater than 35.3 million people worldwide. Current antiretroviral therapy fails to eradicate HIV infection, partly due to the persistence of virus reservoirs. A … Continue reading

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A synthetic antibody with broad antiviral activity

An alternative strategy for creating virus-resistant cells and animals. Continue reading

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Oncolytic virotherapy – in pets?

Oncolytic virotherapy – using viruses to treat cancer – is a hot topic. Continue reading

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Remember what happened last time we "cured" AIDS?

Timothy Brown, the “Berlin patient” was freed of HIV infection via a bone marrow transfusion from a compatible CCR5Δ32 donor in 2007. Last year there was a report of a newborn baby cured by very early drug therapy. The news … Continue reading

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Life in the Post-Antibiotic Era

Last week I was struck by this article in The Verge, Dead meat: how to raise livestock in a post-antibiotic era. I was particularly interested in this because only a week earlier I had been teaching our first year students … Continue reading

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BTV VLPs, OMG

This paper describes plant-based high-level expression of virus-like particles of BTV serotype 8. Continue reading

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Plant viruses as gene delivery vehicles

Getting RNA into cells is a major barrier to future theraputic approaches, so robust systems are urgently needed. Continue reading

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Modified bacteria turn waste into fuel 

“Green” chemistry turns plant waste into fatty acids, and then into fuel. Genetically modified E. coli bacteria are being used to to produce fatty acids from hydrolysates of biomass products such as  switchgrass and forestry residues. There are two ways … Continue reading

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