Combination antiretroviral therapy for HIV-1 infection has resulted in profound reductions in viremia and is associated with marked improvements in morbidity and mortality. Therapy is not curative, however, and prolonged therapy is complicated by drug toxicity and the emergence of drug resistance. Management of clinical drug resistance requires in depth evaluation, and includes extensive history, physical examination and laboratory studies. Appropriate use of resistance testing provides valuable information useful in constructing regimens for treatment-experienced individuals with viremia during therapy. This review outlines the emergence of drug resistance in vivo, and describes clinical evaluation and therapeutic options of the individual with rebound viremia during therapy.
TagsAfrica Agriculture Antibiotics Antivirals Bacteria Bacteriophages Biofilms Biology Biotechnology cancer disease Drugs Education Emerging disease Environment evolution Food Fungi Genetics Google+ Health History HIV/AIDS Immunology infection Influenza Malaria Medicine Microbiology Mycology Parasitology plants Podcast Prions retrovirus RNA Science Tuberculosis University of Leicester Vaccines viaGoogle+ Video Virology virus
Top Posts & Pages
This is a personal weblog. The opinions expressed here represent my own views and not those of my employer or any other organization. Comments on posts represent the opinions of visitors.
MicrobiologyBytes by AJ Cann is licensed under a Creative Commons Attribution-ShareAlike 3.0 Unported License.