Not all viruses are bad viruses

Bacteriophage SpaA1 Two recent interesting papers from Virology:

 

Tools from viruses: Bacteriophage successes and beyond. Virology. 11 Oct 2012, pii: S0042-6822(12)00458-8. doi: 10.1016/j.virol.2012.09.017
Viruses are ubiquitous and can infect any of the three existing cellular lineages (Archaea, Bacteria and Eukarya). Despite the persisting negative public perception of these entities, scientists learnt how to domesticate some of them. The study of molecular mechanisms essential to the completion of viral cycles has greatly contributed to deciphering fundamental processes in biology. Nowadays, viruses have entered the biotechnological era and numerous applications have already been developed. Viral-derived tools are used to manipulate genetic information, detect, diagnose, control and cure infectious diseases, or even design new structural assemblies. With the recent advances in the field of metagenomics, an overwhelming amount of information on novel viruses has become available. As current tools have been historically developed from a limited number of viruses, the potential of discoveries from new archaeal, bacterial and eukaryotic viruses may be limited only by our understanding of the multiple facets of viral cycles.

What is needed for phage therapy to become a reality in Western medicine? Virology. 08 Oct 2012,pii: S0042-6822(12)00456-4. doi: 10.1016/j.virol.2012.09.015
The current status of phage therapy approaches is reviewed and possible hurdles to a practical medical application of bacteriophages in Western countries are identified as discussed at a recent EMBO meeting on “Viruses of Microbes” in Brussels. In view of the growing antibiotic resistance crisis, a coordinated effort by the public health sector is needed to evaluate the potential of phage therapy as an adjunct to antibiotics.

 

 

 

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4 Responses to Not all viruses are bad viruses

  1. B. Golchin says:

    Hi, regarding Bacteriophage I have a question? According to this article, Bacteriophage are very useful & also more powerful than antibiotics, I know that taking antibiotics not only is good for long time but also makes the human’s immune system weak against some bacterias clearly because of the bacteria’s resistant to those antibiotics. While bacteriophage are much more powerful with bacterias simply because it attack the core ( DNA ) of the bacteria & not only that but not hurting human ( host )’s immune system but also help to cure many more immune & bacterial problems. My question is: why knowing these facts we don’t replace antibiotics with bacteriophage ?

  2. B. Golchin says:

    Thanks, the link are very useful specially last one. Another question: can we use Phage therapy for viral disease, as it is virus itself but the mechanism is powerful over bacterial, would it be as effective on viruses system?

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