Weiss, R. (2015) What’s the host and what’s the microbe? The Marjory Stephenson Prize Lecture 2015. Journal of General Virology, 03 July, 2015 doi: 10.1099/jgv.0.000220
The interchange between retroviruses and their hosts is an intimate one because retroviruses integrate proviral DNA into host chromosomal DNA as an obligate step in the replication cycle. This has resulted in the occasional transduction of host genes into retroviral genomes as oncogenes, and also led to the integration of viral genomes into the host germ line that gives rise to endogenous retroviruses. I shall reflect on the evolutionary consequences of these events for virus and host. Then I shall discuss the emergence of non-viral infections of host origin, namely, how malignant cells can give rise to eukaryotic single cell ‘parasites’ that colonize new hosts, and how these in turn have been colonized by host mitochondria.
TagsAfrica Agriculture Antibiotics Antivirals Bacteria Bacteriophages Biofilms Biology Biotechnology cancer disease Drugs Education Emerging disease Environment evolution Food Fungi Genetics Google+ Health History HIV/AIDS Immunology infection Influenza Malaria Medicine Microbiology Mycology Parasitology plants Podcast Prions retrovirus RNA Science Tuberculosis University of Leicester Vaccines viaGoogle+ Video Virology virus
Top Posts & Pages
This is a personal weblog. The opinions expressed here represent my own views and not those of my employer or any other organization. Comments on posts represent the opinions of visitors.
MicrobiologyBytes by AJ Cann is licensed under a Creative Commons Attribution-ShareAlike 3.0 Unported License.