Oncolytic Virotherapy – Where Are We Going?

Oncolytic Viruses The last few years have seen an increased interest in immunotherapy in the treatment of malignant disease. In particular, there has been significant enthusiasm for oncolytic virotherapy, with a large amount of pre-clinical data showing promise in animal models in a wide range of tumour types. How do we move forward into the clinical setting and translate something which has such potential into meaningful clinical outcomes? This article reviews how the field of oncolytic virotherapy has developed so far and what the future may hold.

 

Evidence for Oncolytic Virotherapy: Where Have We Got to and Where Are We Going? (2015) Viruses 7(12), 6291-6312 doi: 10.3390/v7122938

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