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Category Archives: Microbiology
A growing body of evidence has established the importance of the in utero environment on neurodevelopment and long-term cognitive and behavioral outcomes. These data suggest factors that disrupt the tightly regulated in utero environment can modify normal neurodevelopmental processes. Approximately … Continue reading
Chronic immune activation/inflammation and viral persistence in reservoirs are important features of chronic HIV infection, even in patients receiving ART. A recent paper evaluates the involvement of adipose tissue in chronic HIV/SIV infections. Adipose tissue accounts for 15 to 20% … Continue reading
Leptospirosis is a zoonotic bacterial disease that affects vulnerable populations such as rural subsistence farmers and urban slum dwellers. Although leptospirosis causes life-threatening clinical manifestations, such as pulmonary hemorrhage syndrome, and has a worldwide distribution, the key barrier to addressing … Continue reading
Este libro de Principios de virología molecular, que es la traducción de la cuarta edición en inglés ha tenido éxito extraordinario. Constituye una introducción esencial a la virología moderna, desde un enfoque molecular; es una obra clara y concisa, siendo … Continue reading
The gut is an important reservoir for drug-resistant bacteria responsible for life-threatening hospital-acquired infections. Continue reading
Weiss, R. (2015) What’s the host and what’s the microbe? The Marjory Stephenson Prize Lecture 2015. Journal of General Virology, 03 July, 2015 doi: 10.1099/jgv.0.000220 The interchange between retroviruses and their hosts is an intimate one because retroviruses integrate proviral … Continue reading
I’m a bit of a sceptic when it comes to the idea that “phage therapy” is going to save us when the antibiotics fail. There have been enough clinical trails now to show that this cannot be true, at least … Continue reading
Lentiviruses closely related to HIV have infected primates in Africa as far back as 16 million years. Continue reading
While the antibiotic potential of some materials used in historical medicine has been demonstrated, empirical tests of entire remedies are scarce. This is an important omission, because the efficacy of “ancientbiotics” could rely on the combined activity of their various … Continue reading