Category Archives: Prions

What drove the cow mad? Lessons from a fish

For over twenty years scientists have known that a normal protein in the brain, PrP, or prion protein, can become harmful and cause deadly illnesses like Creutzfeldt-Jakob disease (CJD) in humans, and bovine spongiform encephalopathy (BSE) in cattle. What they … Continue reading

Posted in Biology, Health, Medicine, Microbiology, Prions, Science | Tagged , , , , ,

Detecting prions on surgical instruments

Prion diseases are a closely related group of fatal neurodegenerative disorders affecting the central nervous system of humans and animals. They include Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler-Scheinker disease (GSS), fatal familial insomnia (FFI), and kuru in humans; bovine spongiform encephalopathy (BSE) … Continue reading

Posted in Biology, Health, Medicine, Microbiology, Prions, Science | Tagged , , , , ,

Prions in Milk

A decade ago, a new variant form of Creutzfeldt-Jakob disease was identified. The emergence of this prion disease in humans was the consequence of the zoonotic transmission of bovine spongiform encephalopathy through dietary exposure. Since then, the control of human … Continue reading

Posted in Agriculture, Biology, Food, Health, Medicine, Microbiology, Prions, Science | Tagged , , , , , , ,

Prion infectivity found in fat tissues of mice

Researchers have found novel prion infectivity in white and brown fat tissues of mice. Prion diseases, also known as transmissible spongiform encephalopathies, are infectious progressive fatal neurodegenerative diseases which affect humans as well as wild and domestic animals. Distribution of … Continue reading

Posted in Biology, Emerging disease, Food, Health, Medicine, Microbiology, Prions, Science | Tagged , , , , , , ,

vCJD Kills Spanish Mother And Son

The mother of a Spanish man who died from the human form of mad cow disease has also died from the illness. The mother, in her early 60s, died in August 2008. Her son, 41, died in February 2008. Three … Continue reading

Posted in Biology, Genetics, Health, Medicine, Microbiology, Prions, Science | Tagged , , , , , , | 1 Comment

Novel mutation linked to mad cow disease

Researchers from the United States Department of Agriculture have identified a novel mutation in the bovine prion protein gene in a cow confirmed with atypical Bovine Spongiform Encephalopathy (BSE). This is the first report of a confirmed case of BSE … Continue reading

Posted in Agriculture, Biology, Emerging disease, Food, Genetics, Health, Medicine, Microbiology, Prions, Science | Tagged , , , , , , , , ,

A novel approach in the molecular differentiation of prion strains

The origin of the transmissible agent involved in the foodborne epidemic of bovine spongiform encephalopathy (BSE) remains a mystery. It has recently been proposed that this could have been the result of the recycling of an atypical, more probably sporadic, … Continue reading

Posted in Agriculture, Biology, Emerging disease, Food, Microbiology, Prions, Science | Tagged , , , , , ,

Genes contributing to prion pathogenesis

Prion diseases are caused by conversion of a normally folded, non-pathogenic isoform of the prion protein (PrP(C)) to a misfolded, pathogenic isoform (PrP(Sc)). Prion inoculation experiments in mice expressing homologous PrP(C) molecules on different genetic backgrounds displayed different incubation times, … Continue reading

Posted in Biology, Emerging disease, Health, Medicine, Microbiology, Prions, Science | Tagged , , , , , ,

BSE in Korea?

BBC News: At least 35,000 people have taken part in the latest mass protest in South Korea against the government’s decision to allow US beef imports to resume. South Korea used to be a big market for US beef, but … Continue reading

Posted in Agriculture, Biology, Emerging disease, Food, Health, Microbiology, Prions, Science | Tagged , , , , , , ,