Tag Archives: Africa

PLoS Pathogens: Measles Outbreak in Africa – Is There a Link to the HIV-1 Epidemic?

To reduce the risk of contracting measles in areas with high HIV-1 prevalence, WHO recommended that infants receive two doses of measles vaccine, at 6 and 9 months. This regimen was evaluated in Zambia and results published in 2008 showed … Continue reading

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Understanding the spread of rabies

At least 15 million doses of anti-rabies post-exposure prophylaxis are administered annually worldwide, and an estimated 55,000 people die of rabies every year. Over 99% of these deaths occur in developing countries, predominantly in Asia and in Africa where rabies … Continue reading

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World Rabies Day, 28 September

According to official estimates, rabies kills 55,000 people each year, primarily in India, Southeast Asia and Africa. However, the death toll is probably much higher; one report estimates that the number of deaths in some areas is possibly 100 times … Continue reading

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Advances and insights into Rift Valley fever

This article reviews recent research on Rift Valley fever virus (RVFV) infection, encompassing four main areas: epidemiology and outbreak prediction, viral pathogenesis, human diagnostics and therapeutics, and vaccine and therapeutic candidates. RVFV continues to extend its range in Africa and … Continue reading

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Study probes Trypanosoma genome for causes of human infectivity

Sleeping sickness, or Human African Trypanosomiasis, is a disease affecting the health and productivity of poor people in many rural areas of sub-Saharan Africa. The disease is caused by a single-celled flagellate, Trypanosoma brucei, which evades the immune system by … Continue reading

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HIV-associated illness in adolescents in Zimbabwe

Nearly half of adolescents admitted to two public hospitals in Zimbabwe are HIV positive according to a new paper in PLoS Medicine. This study examines the causes of unselected acute hospitalization in adolescents, and serves to highlight the growing crisis … Continue reading

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The Trypanosoma brucei flagellum

Trypanosoma brucei and related subspecies are protozoan parasites that cause African trypanosomiasis in humans and animals, a deadly disease with devastating health and economic consequences. The T. brucei flagellum and flagellar motility are central to disease pathogenesis in the mammalian … Continue reading

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Messing around with malaria

Anopheles gambiae mosquitoes are the principal vectors of human malaria, a disease with devastating consequences for public health and the economic development of disease-endemic countries. The creation of new tools to control vector populations is a focal point of intensive … Continue reading

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Malaria in Burkina Faso – Rocketboom

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