Tag Archives: Antivirals

Getting rid of HIV for good

To assess the efficacy of these elimination strategies in HIV-1 infected patients we must be able to measure the size of the remaining latent reservoir. Continue reading

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Understanding Uncoating

All we need now is a drug to inhibit virus uncoating and we’ve cured the common cold. Well, some of them maybe. Continue reading

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Strategies to Develop Antivirals against Enterovirus 71 

Enterovirus 71 (EV71) is an important human pathogen which can cause severe neurological complications and death in children. The virus caused several outbreaks in the Asia-Pacific region during the past two decades and has been considered a significant public health … Continue reading

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HIV causes AIDS – and how to stop it

A couple of nice papers published recently on the mechanisms by which HIV infection causes AIDS. The first concerns the possible role of bystander apoptosis induction in HIV infection and its role in disease progression. It has become evident that … Continue reading

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Benefit and harm from immunity to respiratory syncytial virus

Respiratory syncytial virus (RSV) is the major cause of bronchiolitis, itself the commonest single cause of hospitalization during infancy. The WHO estimates that RSV infects 34 million children under 5 years of age every year, accounts for 22% of all … Continue reading

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As Good As It Gets? The Problem of HIV Persistence despite Antiretroviral Drugs

Human immunodeficienty virus (HIV) infection is suppressed but not eliminated by antiretroviral drugs. Viral persistence in the face of therapy has been explained by viral latency, lowered effectiveness of drugs in some anatomical sites and cell types, and cell-to-cell spread. … Continue reading

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New insight in the pathobiology of hepatitis B virus infection

In spite of decades of research and successful vaccination strategies, millons of people remain chronically infected with Hepatitis B Virus (HBV) and at risk of death theough liver cancer of liver failure. This recent review looks a recent advances in … Continue reading

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Nanotechnology and the treatment of HIV infection

It seems to be turning into nanotechnology week on MicrobiologyBytes :-)   Nanotechnology and the Treatment of HIV Infection. (2012) Viruses 2012, 4(4), 488-520; doi:10.3390/v4040488 Suboptimal adherence, toxicity, drug resistance and viral reservoirs make the lifelong treatment of HIV infection … Continue reading

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Structural biology of HIV-1 [video]

A video walkthrough of a new review article on HIV structural biology. Continue reading

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