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Tag Archives: Bacteriophages
There are lots of viruses in seawater – but maybe we’re not seeing the whole picture? Continue reading
Pelagibacter ubique is the most successful member of a group of bacteria called SAR11, that jointly constitute about a third of the single-celled organisms in the ocean. But this is not P. ubique’s only claim to fame, for unlike almost … Continue reading
The way populations of bacteriophage interact with populations of bacteria is complex, but vital to understand. Continue reading
Molecular piracy is a biological phenomenon in which one replicon (the pirate) uses the structural proteins encoded by another replicon (the helper) to package its own genome and thus allow its propagation and spread. Such piracy is dependent on a … Continue reading
Two recent interesting papers from Virology: Tools from viruses: Bacteriophage successes and beyond. Virology. 11 Oct 2012, pii: S0042-6822(12)00458-8. doi: 10.1016/j.virol.2012.09.017 Viruses are ubiquitous and can infect any of the three existing cellular lineages (Archaea, Bacteria and Eukarya). Despite … Continue reading
Bacteriophages, particularly the tailed bacteriophages, are the most promiscuous organisms known, playing a continual mix and match with their genes. This paper describes a novel phage genome architecture where one phage genome nestles inside the genome of another phage, similar … Continue reading
Traditional approaches to phage therapy rely on the ability of viruses to kill their bacterial prey. However, the narrow host range or most bacteriophages and the ability of bacteria to become resistant to infection mean that in practice, using phage … Continue reading
This review gives an overview of the current state-of-the-art of bacteriophage therapy. Continue reading