Tag Archives: Bacteriophages

Are we missing half of the viruses in the ocean?

There are lots of viruses in seawater – but maybe we’re not seeing the whole picture? Continue reading

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What is the commonest living thing on Earth? 

Pelagibacter ubique is the most successful member of a group of bacteria called SAR11, that jointly constitute about a third of the single-celled organisms in the ocean. But this is not P. ubique’s only claim to fame, for unlike almost … Continue reading

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Phage-bacteria infection networks

The way populations of bacteriophage interact with populations of bacteria is complex, but vital to understand. Continue reading

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Pirates of the Caudovirales

Molecular piracy is a biological phenomenon in which one replicon (the pirate) uses the structural proteins encoded by another replicon (the helper) to package its own genome and thus allow its propagation and spread. Such piracy is dependent on a … Continue reading

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Not all viruses are bad viruses

Two recent interesting papers from Virology:   Tools from viruses: Bacteriophage successes and beyond. Virology. 11 Oct 2012, pii: S0042-6822(12)00458-8. doi: 10.1016/j.virol.2012.09.017 Viruses are ubiquitous and can infect any of the three existing cellular lineages (Archaea, Bacteria and Eukarya). Despite … Continue reading

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Russian Doll Genetics

Bacteriophages, particularly the tailed bacteriophages, are the most promiscuous organisms known, playing a continual mix and match with their genes. This paper describes a novel phage genome architecture where one phage genome nestles inside the genome of another phage, similar … Continue reading

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Reversing resistance with phage

Traditional approaches to phage therapy rely on the ability of viruses to kill their bacterial prey. However, the narrow host range or most bacteriophages and the ability of bacteria to become resistant to infection mean that in practice, using phage … Continue reading

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The next generation of bacteriophage therapy

This review gives an overview of the current state-of-the-art of bacteriophage therapy. Continue reading

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60 years is a long time in virology

Phage lambda serves as a benchmark for future studies of protein interactions among phage, viruses in general, or large protein assemblies. Yet after 60 years study, much remains unknown. Continue reading

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