Tag Archives: Candida

Microbial Spy Games

Gathering and sharing of information is extremely important in human society. Especially in times of war, the difference between victory and defeat can depend on the ability to obtain, encrypt, and share information, and sophisticated systems have been developed for … Continue reading

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Growth of Candida albicans hyphae

A striking feature of Candida albicans is its ability to grow either as a unicellular budding yeast or in filamentous form. This review describes the signal transduction pathways that induce hyphal growth, the roles of hyphae in the infection process and the cellular mechanisms that operate to promote the extreme growth of hyphae. Continue reading

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A Tale of Two Biofilms

The finding that Candida albicans can form two different types of biofilm is interesting because it shows how signaling pathways may evolve by modifying preexisting signals for entirely new purposes. Continue reading

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CO2 acts as a signalling molecule in Candida albicans

Candida albicans is the predominant fungal pathogen of humans. In healthy individuals C. albicans is a commensal inhabitant of the gastrointestinal, oral and vaginal tracts. C. albicans can cause superficial infections which, although not life threatening, provide discomfort to the … Continue reading

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Statins and Candida

Candida infections are the fourth most common cause of nosocomial blood stream infections and are associated with a significant mortality. Delays in antifungal therapy have been associated with increased hospital costs of over US$6,000 per patient and overall mortality. The … Continue reading

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New Mechanism Fundamental to the Spread of Invasive Yeast

A biofilm is a surface-associated population of microbes that is embedded in a cement of extracellular compounds. This cement is known as matrix. The two main functions of matrix are to protect cells from their surrounding environment, preventing drugs and … Continue reading

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