Tag Archives: Ebola virus

Understanding Ebola Virus Transmission

This short review describes different routes of Ebola virus transmission between people. Continue reading

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A Novel Mechanism of Host Immune Evasion by Ebola Virus

Ebola virus anti-vaccine decoy protein. Sneaky, very sneaky. Continue reading

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Ebola virus glycoprotein and virulence – it's complicated

With Ebola virus in the news again, a new paper in PLoS Pathogens is highly topical. Most Ebola virus species cause severe hemorrhagic fevers with high case fatality rates. However, Reston ebolavirus (REBOV) seems to be apathogenic for humans. While … Continue reading

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Discovery of an Ebolavirus-Like Filovirus in Europe

Filoviruses cause lethal hemorrhagic fever in humans and nonhuman primates. The family Filoviridae includes two genera: Marburgvirus (MARV) and Ebolavirus (EBOVs). MARV was discovered in 1967 in Marburg, Germany during an outbreak in laboratory staff exposed to tissues from monkeys … Continue reading

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Ebola virus entry requires a cholesterol transporter

Infections by the Ebola and Marburg filoviruses cause a rapidly fatal haemorrhagic fever in humans for which no approved antivirals are available. A new paper describes a genome-wide screen of human cells to identify host factors required for Ebola virus entry. Continue reading

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Ebola glycoprotein accumulates in the endoplasmic reticulum

Ebola glycoprotein (GP) is the only virus protein expressed on the surface of Ebola virus and mediates entry into target cells. However, several studies report that GP expression also causes cytotoxicity, although the underlying mechanism remains unknown. GP is also … Continue reading

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Happy Birthday PLoS Pathogens

PLoS Pathogens is two years old, and to celebrate, they’ve just published a list of the top ten papers downloaded from September 2005 to July 2007, so if you need to catch up on your reading: Carrageenan Is a Potent … Continue reading

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