Tag Archives: Escherichia coli

What is it about amyloids?

What is it about amyloids – why are they so widespread in living organisms? Continue reading

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Tumbling and running

Bacteria switch the rotation of their flagellar rotation to search for food by tumbling and running – but how? Continue reading

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E. coli spontaneous mutations

Knowledge of the rate and nature of spontaneous mutation is fundamental to understanding evolutionary and molecular processes. This report analyzes spontaneous mutations accumulated over thousands of generations by wild-type Escherichia coli and a derivative defective in mismatch repair (MMR), the … Continue reading

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How to Make It in the Urinary Tract: A Tutorial by Escherichia coli

Extra-intestinal E. coli (ExPEC) may transition from benign colonization of the enteric and vaginal tracts to cause urinary tract infections (UTIs), septicemia, and meningitis. ExPEC colonization of the lower urinary tract leads to an acute infection of the superficial bladder … Continue reading

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Natural DNA Uptake by E. coli

In the laboratory, we force E.coli to take up DNA all the time. But what really goes on in the environment, or indeed, your gut? Continue reading

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Making a beta-barrel – outer membrane proteins in Gram-negative bacteria

The structural complexities of bacteria are becoming increasingly apparent. Gram-negative bacteria can be divided into several subcellular compartments. There are two aqueous compartments called the cytoplasm and the periplasm. The cytoplasm is enclosed by a phospholipid bilayer called the inner … Continue reading

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Why horizontal gene exchange in Enterobacteria matters

DNA fragments encoding enzymes, transcriptional regulators and virulence factors are fluxing through bacterial taxonomic walls by horizontal gene transfer. These elements often endow environmental and clinical strains of bacteria with new properties, including an enhanced virulence. Lateral genetic exchange, particularly … Continue reading

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Back to the bad old days?

Carbapenems were the last β-lactams retaining near-universal anti-Gram-negative activity, but carbapenemases are spreading, conferring resistance. New Delhi metallo-β-lactamase (NDM) enzymes are the latest carbapenemases to be recognized and since 2008 have been reported worldwide, mostly in bacteria from patients epidemiologically … Continue reading

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Don't go with the flow

The tips of E. coli fimbriae tip forms a hook-chain, ideal for rapid and stable anchoring of bacterial cells to urinary epithelial cells in a rapid flow of urine. Continue reading

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