Tag Archives: Flavivirus

How Zika virus crosses the placenta

Zika virus (ZIKV) causes microcephaly, whereas other related pathogenic flaviviruses do not. To reach the fetal brain, a virus must be transported from the maternal to the fetal circulation, which requires crossing of the placental barrier. This study demonstrates that … Continue reading

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Century-old puzzle of Theiler's hepatitis solved 

For almost 100 years, veterinarians have puzzled over the cause of Theiler’s disease, a mysterious type of equine hepatitis that is linked to blood products and causes liver failure in up to 90% of afflicted animals. A team of scientists … Continue reading

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How Flaviviruses Activate and Suppress the Interferon Response

The flavivirus genus includes viruses with a remarkable ability to produce disease on a large scale. The expansion and increased endemicity of dengue and West Nile viruses in the Americas exemplifies their medical and epidemiological importance. The rapid detection of … Continue reading

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Population movement a critical factor in dengue virus spread

Dengue fever is a major public health problem in many tropical regions of the world. It is a vector-borne disease, transmitted most often by the mosquito Aedes aegypti. According to the WHO, the prevalence of dengue is highest in tropical … Continue reading

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Tick-borne Encephalitis Virus – an emerging zoonosis

Tick-borne encephalitis virus is a Flavivirus, and the causative agent of tick-borne encephalitis (TBE), a potentially fatal neurological infection affecting humans in Europe and Asia. From 1974 to 2003, a 400% increase in TBE morbidity has been observed in Europe, … Continue reading

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