Tag Archives: Genetics

Polintons and network-like evolution of the virus world

Polintons were the first group of eukaryotic double-stranded DNA viruses to evolve from bacteriophages and gave rise to most large DNA viruses and various other selfish genetic elements. Continue reading

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CRISPRs and bacterial pathogenesis

CRISPR-Cas systems have taken microbiology by storm in the last few years. Continue reading

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Human telomeres carry an integrated copy of human herpesvirus 6

Up to half a million people in Britain today may carry a particular form of herpesvirus 6 inherited from a parent in their genetic material. Continue reading

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Burkholderia, evolution and chronic disease

The repertoire of genetic changes in Burkholderia pseudomallei during chronic human infection. Continue reading

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Smaller fleas upon their back to bite them

Rapid advances in genomics lead not only to the rapid growth of sequence databases but to discovery of fundamentally novel types of genetic elements. Continue reading

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No bacterium is an island

Streptococcus pneumoniae has an unusual enzyme that protects foreign DNA taken up during transformation, allowing exchange of pathogenicity islands. Continue reading

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It's not all down to the virus

When you get sick, make sure you take your fair share of the responsibility! Continue reading

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E. coli spontaneous mutations

Knowledge of the rate and nature of spontaneous mutation is fundamental to understanding evolutionary and molecular processes. This report analyzes spontaneous mutations accumulated over thousands of generations by wild-type Escherichia coli and a derivative defective in mismatch repair (MMR), the … Continue reading

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The Epigenetics of Host–Pathogen Interactions

A growing body of evidence points towards epigenetic mechanisms being responsible for a wide range of biological phenomena, from the plasticity of plant growth and development to the nutritional control of caste determination in honeybees and the etiology of human … Continue reading

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