Tag Archives: Genetics

It's not all down to the virus

When you get sick, make sure you take your fair share of the responsibility! Continue reading

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E. coli spontaneous mutations

Knowledge of the rate and nature of spontaneous mutation is fundamental to understanding evolutionary and molecular processes. This report analyzes spontaneous mutations accumulated over thousands of generations by wild-type Escherichia coli and a derivative defective in mismatch repair (MMR), the … Continue reading

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The Epigenetics of Host–Pathogen Interactions

A growing body of evidence points towards epigenetic mechanisms being responsible for a wide range of biological phenomena, from the plasticity of plant growth and development to the nutritional control of caste determination in honeybees and the etiology of human … Continue reading

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The cuddly giant panda – brought to you by bacteria 

The giant panda is one of the most endangered animals in the world, with only 2,500 to 3,000 individuals found in western China. Approximately 7 million years ago, the ancient giant panda was omnivorous, but it shifted from being an … Continue reading

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For life in the hospital, Staph drops excess baggage 

Staphylococcus infections are common in the hospital setting and in the community, but the strains that are prevalent in these two environments differ somewhat. A group in Denmark found that pressure from antibiotic use in hospitals is driving some unexpected evolutionary … Continue reading

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"Where did viruses come from?" (part 4,927)

It’s a question half as old as time. “Where did viruses come from?” Over the last few years there has been quite a lot of activity in this area, in particulraly looking at whether the relatively new-discovered “giruses” (giant DNA … Continue reading

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A Virus Bottleneck

Every year I get excitied and rant at my virology students about how amazing it is that a virus can have more than more host, i.e. for viruses which undergo propagative transmission, replicating in both the “host” and the “vector”. … Continue reading

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Field guide to the Epstein-Barr virus

Researchers have published the first annotated atlas of the Epstein-Barr virus genome, creating the most comprehensive study of how the virus genome interacts with its human host during a latent infection. Epstein-Barr virus (EBV), which is thought to be responsible … Continue reading

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We know what retroviruses were up to 407 million years million years ago

The deep history of retroviruses is still obscure. Retroviruses can leave integrated copies within their hosts’ genomes, providing a fossil record for studying their long-term evolution. Endogenous forms of foamy viruses, complex retroviruses known to infect only mammalian species, appear … Continue reading

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