Tag Archives: HCV

Targeting the host rather than the virus

Chronic hepatitis C virus infection is a major cause of liver cirrhosis and hepatocellular carcinoma and there is no vaccine to prevent HCV infection. Continue reading

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It's not all down to the virus

When you get sick, make sure you take your fair share of the responsibility! Continue reading

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Rising numbers of hepatitis C patients treated for liver disease

216,000 people in the UK are now thought to be infected with hepatitis C virus (HCV) according to the UK Health Protection Agency (HPA). Thousands of people were also infected accidentally through contaminated blood products in the 1970s and 1980s. … Continue reading

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Experimental hepatitis C vaccine tested

Is an effective vaccine for hepatitis C virus getting closer? Continue reading

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Hepatitis C virus (HCV) receptor identified

New research shows that Niemann-Pick C1–like 1 (NPC1L1) cholesterol uptake receptor is an HCV cell entry factor that functions after binding, at or before fusion. Together with the facts that NPC1L1 is a cellular cholesterol receptor, the HCV particle is … Continue reading

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Hepatitis B and C Viruses and Hepatocellular Carcinoma

Hepatocarcinogenesis (liver cancer) is, and will continue to be a major worldwide health problem. With chronic HBV and HCV infections being responsible for a significant proportion of HCC cases, the development of new and relevant cell culture and animal models … Continue reading

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Hepatitis C virus controls interferon production through PKR activation

In response to invasion with bacterial or viral pathogens, cells are able to mount an immediate immune response through their ability to use specialized cellular molecules, referred to as pattern recognition receptors or PRRs, to detect unusual DNA, ssRNA or … Continue reading

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How the antiviral protein viperin works

Lipid droplets consist of a core of neutral lipids surrounded by an outer phospholipid monolayer and associated proteins. These organelles are thought to be generated when neutral lipids accumulate in the endoplasmic reticulum (ER) bilayer. Recently, lipid droplets have been … Continue reading

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Update on HBV and HCV Therapy

Chronic hepatitis B virus (HBV) infection affects about 400 million people around the globe, being one of the most common infectious diseases and among the world’s leading causes of death. Antiviral therapy of chronic hepatitis B (CHB) aims to improve … Continue reading

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