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Tag Archives: HIV/AIDS
HIV has spread at an alarming rate in South Africa, making it the country with the highest number of HIV infections. Several studies have investigated the histories of HIV-1 subtype C epidemics but none have done so in the context … Continue reading
It may be more effective to develop HIV treatments that prevent cell-to-cell infection by the virus. Continue reading
Chronic immune activation/inflammation and viral persistence in reservoirs are important features of chronic HIV infection, even in patients receiving ART. A recent paper evaluates the involvement of adipose tissue in chronic HIV/SIV infections. Adipose tissue accounts for 15 to 20% … Continue reading
CCR5 deficiency predisposes to fatal outcomes in influenza virus infection. Continue reading
Why does the immune system fail to clear some virus (and other infections) and allow a state of chronic infection to occur? Continue reading
Two papers provide a more detailed structural picture of how HIV Rev works. Continue reading
A theoretical basis why artificial virus-like particles (VPLs) with a high density of envelope spikes might make a safe and efecting prophylactic vaccine against HIV. Continue reading
More than three decades after the discovery of HIV, AIDS remains a major public health problem affecting greater than 35.3 million people worldwide. Current antiretroviral therapy fails to eradicate HIV infection, partly due to the persistence of virus reservoirs. A … Continue reading