Tag Archives: Immunology

Fifty Shades of Immune Defence

Innate and adaptive immunity are no longer black and white, there are increasing shades of grey. Continue reading

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Rotavirus Roundup

Several interesting papers on responses to rotavirus infection have been published recently, so I thought I’d round them up in one place. Continue reading

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It's not all down to the virus

When you get sick, make sure you take your fair share of the responsibility! Continue reading

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A novel role for lipid droplets in the antibacterial response

Histones bound to lipid droplets can protect cells against bacteria without causing the harm normally associated with the presence of free histones. Continue reading

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How HIV Sneaks aboard Mature Dendritic Cells 

HIV, the virus that causes AIDS, has an extensive repertoire of tricks that it uses to evade, manipulate, and subvert the human immune system. Perhaps most insidious is the virus’s ability to turn the immune system’s defensive tactics to its … Continue reading

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Vaccines: From Empirical Development to Rational Design

Infectious diseases are responsible for an overwhelming number of deaths worldwide and their clinical management is often hampered by the emergence of multi-drug-resistant strains. Therefore, prevention through vaccination currently represents the best course of action to combat them. However, immune … Continue reading

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A virological view of innate immune recognition

The innate immune system uses multiple strategies to detect viral infections. Because all viruses rely on host cells for their synthesis and propagation, the molecular features used to detect viral infections must be unique to viruses and absent from host … Continue reading

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How parasitic worms cure inflammatory bowel disease

Inflammatory bowel disease sufferers (IBD, including Crohn’s disease and ulcerative colitis) experience a variety of unpleasant symptoms such as abdominal pain, vomiting, diarrhoea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis and weight loss. The causes of these … Continue reading

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Bacterial infections and Alzheimer's disease – more similar than you think?

Microbial infections are among the worst human diseases and cause millions of deaths per year over the world. Antibiotics are used to treat infections and have saved more lives than any other drug in human history. However, due to extended … Continue reading

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