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Tag Archives: Malaria
Malaria kills thousands of times more people than Ebola virus each year. Continue reading
Mosquitoes infected with the malaria parasite Plasmodium falciparum are significantly more attracted to human odors than uninfected mosquitoes. Continue reading
Malaria, toxoplasmosis, and related diseases are caused by infection with unicellular parasites called Apicomplexa. Their name refers to the elaborate invasion machinery that occupies the apical end of the parasite cell. This apparatus allows the parasite to force its way … Continue reading
The parasite Plasmodium falciparum is the causative agent of severe malaria in humans, killing somewhere between 600,000 and 1.2 million people each year. The complex life cycle includes an asexual proliferation within human erythrocytes, characterised by three distinct stages: rings, … Continue reading
A paper in this week’s PLoS Medicine compares the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human and nonhuman parasite species, including Plasmodium falciparum, Plasmodium berghei and Plasmodium yoelii. These results provide … Continue reading
Protozoan parasites cause tremendous human suffering worldwide, but treatment strategies are limited. The recognition of social behaviors by parasitic protozoa could provide new approaches to important diseases. Continue reading
The malaria parasite has a chloroplast which is a holdover from its algal past. The fascinating biology of this organelle and its promise for treatment is discussed in a new study. Continue reading
Humans have suffered from the burden of malarial infections for thousands of years, and the disease has influenced human evolution and history. Our ability to counter these vulnerabilities is hampered by the modest number of drug targets and our limited understanding of parasite biology. Continue reading