Tag Archives: norovirus

Can we prevent norovirus infections?

Each year, noroviruses cause over 200,000 deaths and a global economic burden of US$64 billion. A highly contagious virus that most people will contract 5 times in their lifetime, the most serious outcomes of the disease – hospitalization and death … Continue reading

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A virus emerging before our eyes 

When I wrote about the high incidence of norovirus infections in the UK recently – http://goo.gl/TUdko – a commenter helpfully pointed to a paper published in Eurosurveillance on January 3 described a new variant of norovirus called Sydney 2012. The UK HPA … Continue reading

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Norovirus – making a fuss about nothing? 

For all the media attention on the UK norovirus “epidemic” over the past few weeks, current figures recently released by the UK Health Protection Agency (see: http://goo.gl/KLNhl ) suggest that this norovirus season (“”winter vomiting”) is not particularly unusual. HPA … Continue reading

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Norovirus – there's a lot of it about 

Recent data suggest that cases of norovirus infection, which are usually highest after Christmas, are high for this time of year. According to data available up to December 2 2012, there have been 2,313 confirmed laboratory reports (which is 64% … Continue reading

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Disruption of gut microbiota following Norovirus infection

The human gut microbiota is a complex bacterial community that is relatively stable over time. Disruption of the microbiota can increase the risk for several health complications, including loss of colonization resistance against bacterial pathogens and predisposition to autoimmune and … Continue reading

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Norovirus Immunity and the Great Escape

Noroviruses (NoVs), members of the Calicivirus family, are small, positive-polarity RNA viruses and the most important cause of human foodborne viral gastroenteritis worldwide. These viruses cause gastrointestinal disease, resulting in recurrent bouts of vomiting and diarrhea that typically last 24–48 … Continue reading

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Norovirus-host interaction and blood group antigens

Noroviruses are a major cause of epidemic acute gastroenteritis affecting millions of people worldwide. Infection by these viruses relies on recognition of human histo-blood group antigens as receptors for attachment, an early infection event that most likely controls host susceptibility and resistance. Continue reading

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Beware the buffet

Even if we have never succumbed to it, we are all familiar with the sickness caused by noroviruses due to high-profile media coverage of outbreaks in various closed communities, such as hospitals and cruise ships. In this article in Microbiology … Continue reading

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Pathogenesis of Noroviruses

Human noroviruses in the family Caliciviridae are a major cause of epidemic gastroenteritis. They are responsible for at least 95% of viral outbreaks and over 50% of all outbreaks worldwide. Transmission of these highly infectious plus-stranded RNA viruses occurs primarily … Continue reading

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