Tag Archives: paramyxoviruses

Cells fight back against virus factories

This week I’ve been talking to first year students about cell biology, discussing how much the environment of the cell varies from one site to another within the cell. Viruses “know” this and much virus replication is localized at particular … Continue reading

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Emerging Paramyxoviruses – Receptor Tropism and Zoonotic Potential

Emerging infectious disease events are dominated by zoonoses: infections that are naturally transmissible from animals to humans or vice versa. A worldwide survey of ~5,000 bat specimens identified 66 novel paramyxovirus species – more than double the existing total within … Continue reading

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How immunity to RSV develops in childhood but deteriorates in adults

A leading infectious cause of severe respiratory disease in infants, respiratory syncytial virus (RSV), is also a major cause of respiratory illness in the elderly. Approved vaccines do not yet exist, and despite the development of partial immunity following infection … Continue reading

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Morbillivirus Infections: An Introduction

Research on morbillivirus infections has led to exciting developments in recent years. Continue reading

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Paramyxovirus polymerase: transcription or replication?

How does the paramyxovirus polymerase decide on transcription or replication? Continue reading

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Drawing the line – they shall not pass?

The Wallace Line may not protect Australia from the spread of viruses. Continue reading

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Benefit and harm from immunity to respiratory syncytial virus

Respiratory syncytial virus (RSV) is the major cause of bronchiolitis, itself the commonest single cause of hospitalization during infancy. The WHO estimates that RSV infects 34 million children under 5 years of age every year, accounts for 22% of all … Continue reading

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Microbiology Twitter Journal Club #microtwjc – tonight, 8pm BST

twitter.com/search/%23microtwjc Read: Bats host major mammalian paramyxoviruses. (2012) Nature Communications 3, Article number: 796 doi:10.1038/ncomms1796 The large virus family Paramyxoviridae includes some of the most significant human and livestock viruses, such as measles-, distemper-, mumps-, parainfluenza-, Newcastle disease-, respiratory syncytial … Continue reading

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Pathogenesis of respiratory syncytial virus

While affecting all age groups, respiratory syncytial virus (RSV) infections can be particularly severe in infants, who develop functionally distinct immune responses, as well as in immunocompromised individuals. The extent to which environmental, viral and host factors contribute to the … Continue reading

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