Tag Archives: paramyxoviruses

The nucleocapsid protein of measles virus blocks host interferon response

Measles virus (MV) belongs to the genus Morbillivirus of the family Paramyxoviridae. A number of paramyxoviruses inhibit host interferon (IFN) signaling pathways in host immune systems by various mechanisms. Inhibition mechanisms have been described for many paramyxoviruses. Although there are … Continue reading

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Negative strand RNA viruses – the state of the art

It was my priveledge to work with Brian Mahy many years ago. Brian has just retired as long-serving Editor of Virus Research, and his swansong is an excellent special issue on negative strand RNA viruses – an important read for … Continue reading

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Measles virus fusion and entry

“Trigger microdomains” at the interface of paramyxovirus fusion complexes constitute attractive targets for the design of novel antivirals. Functional and biochemical analyses of the fusion complex may allow the development of future therapeutics and prophylactics against these viruses. Continue reading

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Human metapneumovirus in wild mountain gorillas

The world’s remaining 786 mountain gorillas (Gorilla beringei beringei) live in 2 parks in Rwanda, Uganda, and the Democratic Republic of the Congo. An ecotourism industry for viewing human-habituated mountain gorillas in the wild is thriving in all 3 countries. … Continue reading

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Fabulous Measles Timeline

Fabulous Measles Timeline from History of Vaccines. Continue reading

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Molecular Epidemiology and Evolution of Human Respiratory Syncytial Virus and Human Metapneumovirus

Many human viruses undergo a turnover and replacement of predominant lineages with emergent strains appearing. Respiratory syncytial virus is a particularly troublesome pathogen we still haven’t been able to make an effective vaccine against. Continue reading

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