Tag Archives: Plasmodium

Effect of antimalarial drugs on the parasite life cycle

A paper in this week’s PLoS Medicine compares the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human and nonhuman parasite species, including Plasmodium falciparum, Plasmodium berghei and Plasmodium yoelii. These results provide … Continue reading

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Evolving protection against malaria

The asexual erythrocytic phase of the life cycle of Plasmodium falciparum produces the clinical symptoms, disease and pathology associated with malaria. During this phase, merozoites released from schizont-infected erythrocytes invade uninfected erythrocytes. Invasion depends on distinct molecular interactions between ligands … Continue reading

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Regulatory T cells control onset and course of malaria

Malaria is a major global health problem responsible for more than one million deaths annually. Severity of malaria disease is associated with the inability of host immune cells to efficiently eliminate malaria parasites from the blood. Little is known about … Continue reading

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