Tag Archives: Prions

An anti-prion system that cures infected cells

A system to cure prion infection of cells in yeast may have applications in human diseases. Continue reading

Posted in Microbiology | Tagged , , , | Leave a comment

In case you forgot – we're still fighting vCJD

A new test for asymptomatic vCJD. Continue reading

Posted in Uncategorized | Tagged , , , , , ,

How, exactly, do prion proteins cause disease?

Most of the major questions about prions seem now to have been answered, but one big issue still remains – how exactly do these proteins cause disease? Continue reading

Posted in Uncategorized | Tagged , , , , , ,

Virology Weekly Newsletter 22.03.2013 – Bumper End of Term Prion Edition!

A weekly newsletter for students taking my virology course. Continue reading

Posted in Uncategorized | Tagged , , , , , ,

Tis some visitor I muttered, tapping at my chamber door

Crows fed on prion-infected brains from mice can transmit these infectious agents in their faeces and may play a role in the geographic spread of diseases caused by prions, such as chronic wasting disease or scrapie. The new research shows … Continue reading

Posted in Uncategorized | Tagged , , ,

Five Questions on Prion Diseases

Nice short review the current knowledge on five issues relevant to prion diseases: How do prions enter the body? How do prions reach the central nervous system? How do prions damage the CNS? Do mammals have an antiprion defense system? … Continue reading

Posted in Uncategorized | Tagged , , , ,

The Role of Cofactors in Prion Propagation and Infectivity

Prions are self-replicating proteins which in some circumstances causes infections such as mad cow disease. Although they do not contain any nucleic acids, they do require certain co-factors to replicate. Continue reading

Posted in Uncategorized | Tagged , , ,

Mutation and Selection of Prions

Propagation, mutation, and selection of prions in cultured cells. Continue reading

Posted in Uncategorized | Tagged , , , ,

Biochemical Properties of Highly Neuroinvasive Prion Strains

Prion diseases are fatal neurodegenerative disorders that are also infectious. Prions are composed of a misfolded, aggregated form of a normal cellular protein that is highly expressed in neurons. Prion-infected individuals show variability in the clinical signs and brain regions … Continue reading

Posted in Uncategorized | Tagged , , , , ,