Tag Archives: Science

T cell exhaustion during persistent viral infections

Why does the immune system fail to clear some virus (and other infections) and allow a state of chronic infection to occur? Continue reading

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Life in Our Phage World

“[the] molecular biology of higher organisms does not stand on the shoulder of giants, but on the shoulder of dwarfs like phage T4 and lambda.” Continue reading

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Paramyxovirus polymerase: transcription or replication?

How does the paramyxovirus polymerase decide on transcription or replication? Continue reading

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Coronavirus Cell Entry Requires Proteolysis of the S Protein

Different coronaviruses use different proteases to cleave the the S protein for cell entry. Continue reading

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Poliovirus replication – many generations per cell

Viruses with RNA genomes can multiply quickly, but not very accurately. This means that errors, or mutations, occur when the RNA is copied to create new viruses. The advantage of this rapid, but mistake-filled, RNA replication process is that some … Continue reading

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The arthropod origins of RNA viruses

A new paper in eLife describes the genetic diversity and novel genome structures of RNA viruses from arthopods, shedding new light on the ancestry and evolutionary history of plant and animal RNA viruses.   Unprecedented genomic diversity of RNA viruses … Continue reading

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Understanding Ebola Virus Transmission

This short review describes different routes of Ebola virus transmission between people. Continue reading

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Polintons and network-like evolution of the virus world

Polintons were the first group of eukaryotic double-stranded DNA viruses to evolve from bacteriophages and gave rise to most large DNA viruses and various other selfish genetic elements. Continue reading

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Bacterial Flagella: Twist, Stick or Dodge

The bacterial flagellum is an intricate multi protein assembly with many functions. Continue reading

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