Tag Archives: Virology

Latency in Herpes Simplex Virus 1

Herpes simplex virus 1 (HSV-1) is a neurotropic virus that establishes a life-long latent infection in the trigeminal ganglia (TG) of the infected human host. From time to time the virus asymptomatically or symptomatically reactivates from the latency stage producing … Continue reading

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The debt we owe to retroviruses

It was already known that genes inherited from ancient retroviruses are essential to the formation of the placenta in mammals. Now it appears that genes with retrovirus origins may also be responsible for the more developed muscle mass seen in … Continue reading

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Fighting Rabies in China

China has the second highest number of reported rabies cases in the world, but numbers of human deaths have been decreasing. According to the WHO, the Chinese authorities are forecasting national rabies elimination by 2025. Most of the cases are … Continue reading

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The Ins and Outs of Multipartite Plant Viruses

Viruses possessing a non-segmented genome require a specific recognition of their nucleic acid to ensure its protection in a capsid. A similar feature exists for viruses having a segmented genome, usually consisting of viral genomic segments joined together into one … Continue reading

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The Buzz about Honey Bee Viruses

This short review presents current understanding of the role of viruses on honey bee health and address some overarching questions in honey bee virology. Why Should I Be Concerned about Honey Bee Colony Losses and What Is Colony Collapse Disorder … Continue reading

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Assessing the global threat from Zika virus

First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key … Continue reading

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Emerging Paramyxoviruses – Receptor Tropism and Zoonotic Potential

Emerging infectious disease events are dominated by zoonoses: infections that are naturally transmissible from animals to humans or vice versa. A worldwide survey of ~5,000 bat specimens identified 66 novel paramyxovirus species – more than double the existing total within … Continue reading

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HTLV-1 Replication: An Update

I spent more than 10 years working on HTLV, the first human retrovirus to be discovered, but it was a long time ago (propably before most of the people reading this now were born :-) It’s good to get an … Continue reading

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Towards a cure for herpesvirus infection with CRISPR/Cas9

Most adults carry multiple herpesviruses. Following the initial acute infection, these viruses establish life-long infections in their hosts and cause cold sores, keratitis, genital herpes, shingles, infectious mononucleosis, and other diseases. Some herpesviruses can cause cancer in man. During the … Continue reading

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